chemotherapy

Science

FDA clears IND for clinical trial testing switchable CAR-T therapy in patients with autoimmune diseases, without chemotherapy

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their…

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Combination of dual-targeted therapies and chemotherapy shows high response rates in BRAF-mutated metastatic colorectal cancer

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefitted from first-line treatment with the targeted therapies encorafenib and…

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Tongue cancer organoids reveal secrets of chemotherapy resistance

Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers…

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Science

Study finds chemotherapy antidote could improve recovery after chemotherapy-induced kidney toxicity

An FDA-approved medication called glucarpidase could serve as an antidote to kidney toxicity in patients receiving the chemotherapy drug methotrexate…

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Science

Charting a path toward overcoming glioblastoma resistance to chemotherapy

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used…

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Science

Generic platinum chemotherapy shortages did not increase deaths

During a shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023, there was no…

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